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Number of items: 15.

Article

De Marchi, Fabiola; Franjkic, Toni; Schito, Paride; Russo, Tommaso; Nimac, Jerneja; Chami, Anna A.; Mele, Angelica; Vidatic, Lea; Kriz, Jasna; Julien, Jean-Pierre; Apic, Gordana; Russell, Robert B.; Rogelj, Boris; Cannon, Jason R.; Baralle, Marco; Agosta, Federica; Hećimović, Silva; Mazzini, Letizia; Buratti, Emanuele; Munitic, Ivana (2023) Emerging Trends in the Field of Inflammation and Proteinopathy in ALS/FTD Spectrum Disorder. Biomedicines, 11 (6). ISSN 2227-9059

Dominko, Kristina; Rastija, Ana; Smiljanic, Kosara; Mladenovic, Aleksandra; Lešnjaković, Lucija; Kanazir, Selma; Milanovic, Desanka; Hećimović, Silva (2022) Amyloid-ß plaque formation and BACE1 accumulation in the brains of a 5xFAD Alzheimer's disease mouse model is associated with altered distribution and not proteolysis of BACE1 substrates Sez6 and Sez6L. Mechanisms of Ageing and Development, 207 . p. 111726. ISSN 00476374

Dominko, Kristina; Rastija, Ana; Sobočanec, Sandra; Vidatic, Lea; Meglaj, Sarah; Lovinčić Babić, Andrea; Hutter-Paier, Birgit; Colombo, Alessio-Vittorio; Lichtenthaler, Stefan F.; Tahirović, Sabina; Hećimović, Silva (2021) Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation. International journal of molecular sciences, 22 (24). ISSN 1422-0067

Van Hoecke, L.; Van Cauwenberghe, C.; Dominko, Kristina; Van Imschoot, G.; Van Wonterghem, E.; Castelein, J.; Xie, J.; Claeys, W.; Vandendriessche, C.; Kremer, A; Borghgraef, P; De Rycke, R.; Hećimović, Silva; Vandenbroucke, R.E. (2021) Involvement of the Choroid Plexus in the Pathogenesis of Niemann-Pick Disease Type C. Frontiers in Cellular Neuroscience, 15 . ISSN 1662-5102

Colombo, A; Dinkel, L.; Müller, S. A.; Sebastian Monasor, L.; Schifferer, M.; Cantuti-Castelvetri, L.; König, J.; Vidatic, Lea; Bremova-Ertl, T.; Lieberman, A.; Hećimović, Silva; Simons, M.; Lichtenthaler, S. F.; Strupp, M.; Schneider, S. A.; Tahirović, S. (2021) Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia. Nature communications, 12 (1). ISSN 2041-1723

Avrahami, Limor; Paz, Rom; Dominko, Kristina; Hećimović, Silva; Bucci, Cecilia; Eldar-Finkelman, Hagit (2020) GSK-3-TSC axis governs lysosomal acidification through autophagy and endocytic pathways. Cellular signalling, 71 . ISSN 0898-6568

Čaušević, Mirsada; Dominko, Kristina; Malnar, Martina; Vidatic, Lea; Čermak, Stjepko; Pigoni, Martina; Kuhn, Peer-Hendrik; Colombo, Alessio; Havas, Daniel; Flunkert, Stefanie; McDonald, Jessica; Gunnersen, Jenny M; Hutter-Paier, Birgit; Tahirovic, Sabina; Windisch, Manfred; Krainc, Dimitri; Lichtenthaler, Stefan F; Hećimović, Silva (2018) BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains. PLoS One, 13 (7). ISSN 1932-6203

Košiček, Marko; Gudelj, Ivan; Horvatić, Anita; Jović, Tanja; Vučković, Frano; Lauc, Gordan; Hećimović, Silva (2018) N-glycome of the lysosomal glycocalyx is altered in Niemann-Pick Type C disease model cells. Molecular & cellular proteomics, 17 (4). pp. 631-642. ISSN 1535-9476

Čermak, Stjepko; Košiček, Marko; Mladenovic-Djordjevic, Aleksandra; Smiljanic, Kosara; Kanazir, Selma; Hećimović, Silva (2016) Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins. PLoS One, 11 (11). e0167428-1-e0167428-17. ISSN 1932-6203

Malnar, Martina; Hećimović, Silva; Mattsson, Niklas; Zetterberg, Henrik (2014) Bidirectional links between Alzheimer's disease and Niemann-Pick type C disease. Neurobiology of disease, 72 . pp. 37-47. ISSN 0969-9961

Dražić, Tonko; Molčanov, Krešimir; Sachdev, Vinay; Malnar, Martina; Hećimović, Silva; Patankar, Jay V.; Obrowsky, Sascha; Levak-Frank, Sanja; Habuš, Ivan; Kratky, Dagmar (2014) Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors. European Journal of Medicinal Chemistry, 87 . pp. 722-734. ISSN 0223-5234

Košiček, Marko; Hećimović, Silva (2013) Phospholipids and Alzheimer’s disease: alterations, mechanisms and potential biomarkers. International Journal of Molecular Sciences, 14 (1). pp. 1310-1322. ISSN 1661-6596

Malnar, Martina; Košiček, Marko; Lisica, Ana; Posavec, Melanija; Krolo, Ana; Njavro, Jasenka; Omerbašić, Damir; Tahirović, Sabina; Hećimović, Silva (2012) Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells. Biochimica et biophysica acta-molecular basis of disease, 1822 (8). pp. 1270-1283. ISSN 0925-4439

von Einem, Bjorn; Weber, Petra; Wagner, Michael; Malnar, Martina; Košiček, Marko; Hećimović, Silva; von Arnim, Christine; Schneckenburger, Herbert (2012) Cholesterol dependent energy transfer between fluorescent proteins - insights into protein proximity of APP and BACE1 in different membranes in Niemann-Pick type C disease cells. International Journal of Molecular Sciences, 13 (12). pp. 15801-15812. ISSN 1661-6596

Malnar, Martina; Košiček, Marko; Mitterreiter, Stefan; Omerbašić, Damir; Lichtenthaler, Stefan F.; Goate, Alison; Hećimović, Silva (2010) Niemann Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the β-secretase pathway. Biochimica et biophysica acta : molecular basis of diseas, 1802 (7/8). pp. 682-691. ISSN 0925-4439

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