Kovačić, Ines; Perić, Lorena; Fafanđel, Maja (2012) Tissue-specific response of acid DNase activity in mussel Mytilus galloprovincialis exposed to mixed pollutants in sea-water organic extracts. In: Kopjar, Nevenka, (ed.) Arhiv za higijenu rada i toksikologiju-Archives of industrial hygiene and toxicology. Zagreb, Institut za medicinska istraživanja medicinu rada-Institute for Medical Research and Occupational Health, p. 31 .
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Abstract
New biomarkers of high sensitivity and low cost are widely investigated for marine biomonitoring purposes. Our previous investigations showed that the exposure of mussels to individual model marine pollutants causes the increase of acid DNase activity in hematocytes and hepatocytes indicating acid DNase activity as a promising biomarker. For further validation mussels were exposed to composite organic extracts of seawater from Adriatic (VRANJIC, industrial area – high potential toxicity, RIJEKA, harbor – moderate potential toxicity, PLOČE, small rural – low potential toxicity) and acid DNase activity was measured in gills and digestive gland. The patterns of influences in both tissues are site specific and related to different potential toxicity of sea-water extracts. In referent mussels acid DNase activity was higher in gills than in digestive gland. The extract from station with low potentional toxicity (PLOČE) did not induce statistically significant change the acid DNase activity in either tissue. Enzyme activity changed in gills of mussels exposed to extract with moderate potential toxicity (RIJEKA) and in digestive gland of mussels exposed to extracts with high potential toxicity (VRANJIC). In both cases enzyme activity increased already after 3 h, remained for 48 h and discriminate stations according to potential toxicity of organic extracts. Advantages/disadvantages of using acid DNase activity in mussel gills and/or digestive gland as biomarker of toxic pollutant presence are discussed.
| Item Type: | Conference or workshop item published in conference proceedings (UNSPECIFIED) | ||||||||
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| Uncontrolled Keywords: | mussel; Acid DNase; marine pollutant; biomarker | ||||||||
| Subjects: | NATURAL SCIENCES > Interdisciplinary Natural Sciences NATURAL SCIENCES > Interdisciplinary Natural Sciences > Marine Science |
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| Divisions: | Center for Marine Research | ||||||||
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| Depositing User: | Lorena Perić | ||||||||
| Date Deposited: | 10 Dec 2013 11:11 | ||||||||
| URI: | http://fulir.irb.hr/id/eprint/1207 |
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