Solvatomorphic Diversity in Coordination Compounds of Copper(II) with l-Homoserine and 1,10-Phenanthroline: Syntheses, Crystal Structures and ESR Study

Vušak, Darko; Šimunović Letić, Marta; Tašner, Marina; Matković-Čalogović, Dubravka; Jurec, Jurica; Prugovečki, Biserka; Žilić, Dijana (2024) Solvatomorphic Diversity in Coordination Compounds of Copper(II) with l-Homoserine and 1,10-Phenanthroline: Syntheses, Crystal Structures and ESR Study. Molecules, 29 (23). pp. 5621-5635. ISSN 1420-3049

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Official URL: https://www.mdpi.com/1420-3049/29/23/5621

Abstract

Abstract: In this study, we report the syntheses, crystal structures and magnetic properties of ternary copper(II) coordination compounds with L-homoserine (L-Hhser) and 1,10-phenanthroline (phen). Six new coordination compounds were obtained: [Cu(L-hser)(H2O)(phen)]2SO4 ·5H2O (1·5H2O), [Cu(µ-L-hser)(H2O)(phen)][Cu(L-hser)(H2O)(phen)]3 (SO4 )2 ·12H2O (2·12H2O), {[Cu(µ-Lhser)(H2O)(phen)][Cu(µ-L-hser)(phen)]SO4 ·6H2O}n (3·6H2O), {[Cu(µ-L-hser)(H2O)(phen)]2SO4 ·3H2O}n (4·3H2O), [Cu(L-hser)(H2O)(phen)][Cu(L-hser)(CH3OH)(phen)]SO4 ·4H2O (5·4H2O) and {[Cu(Lhser)(CH3OH)(phen)][Cu(µ-L-hser)(phen)]SO4 ·5CH3OH}n (6·5CH3OH). It was shown that slight differences in water content in the synthetic mixtures highly influence the final product, so in some cases, two or three different products were obtained. The compounds were characterized by singlecrystal X-ray diffraction and ESR spectroscopy. Crystal packings are based on intensive networks of hydrogen bonds and π interactions. Most water solvent molecules in these microporous compounds are found in discrete pockets (1·5H2O, 2·12H2O, 3·6H2O, 4·3H2O). In 5·4H2O, water molecules are packed in pockets and 1D channels and in 6·5CH3OH methanol solvent molecules form 1D channels. ESR spectroscopy measured from room down to liquid nitrogen temperature was used for local magnetic characterization of copper centers. The spin Hamiltonian parameters obtained from the spectral simulation revealed copper coordination geometry that is in agreement with the structural results. Furthermore, ESR spectra revealed no significant exchange coupling between copper ions. 3·6H2O showed pronounced antiproliferative activity toward human colon cancer cell lines (HCT116), human breast cancer cell line (MCF-7) and human lung cancer cell lines (H460).

Item Type:

Article

Uncontrolled Keywords:

crystal structures; ESR spectroscopy; magnetism; single-crystal X-ray diffraction; solid state; solvatomorphism; structural transformations

Subjects:

NATURAL SCIENCES > Physics > Condensed Matter Physics

Divisions:

Division of Physical Chemistry

Projects:

Project title	Project leader	Project code	Project type
Molekulski magnetizam u naprednim čvrstim i mekim materijalima	Dijana Žilić	MOMENT HrZZ-IP-2022-10-9292	Research project
Centar izvrsnosti u kemiji - CIuK-CIuK	Josip Požar; Mirta Rubčić; Ivana Biljan	KK.01.1.1.02.0016	EK
Sinteza i strukturna karakterizacija organskih i kompleksnih spojeva; struktura proteina	Biserka Prugovečki	UNSPECIFIED	UNSPECIFIED