A contribution to the understanding of ocular and cerebrospinal fluid dynamics in astronauts during long-lasting spaceflight

Orešković, Darko; Radoš, Milan; Klarica, Marijan (2021) A contribution to the understanding of ocular and cerebrospinal fluid dynamics in astronauts during long-lasting spaceflight. Croatian Medical Journal, 62 (4). pp. 420-421. ISSN 0353-9504

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Abstract

Zhang and Hargens reviewed the knowledge on visual impairment intracranial pressure (VIIP) syndrome in astronauts, a condition that arises as a consequence of long-lasting spaceflight. However, the etiology and pathophysiology of VIIP syndrome remain unclear and only hypothetical. A direct transmission of elevated ICP from the intracranial to the intraocular compartment through the perioptic subarachnoid space should lead to optic nerve sheath distension and disk edema. Therefore, elevated pressure gradient across the lamina cribrosa caused by chronic, gently elevated ICP should finally cause posterior-globe flattening, disk edema, choroid folds, and a hyperoptic shift.

Item Type:	Article
Uncontrolled Keywords:	cerebrospinal fluid; ocular fluid dynamics; astronauts
Subjects:	BIOMEDICINE AND HEALTHCARE > Basic Medical Sciences
Divisions:	Division of Molecular Biology
Depositing User:	Ana Zečević
Date Deposited:	23 Feb 2024 13:16
URI:	http://fulir.irb.hr/id/eprint/8628
DOI:	10.3325/cmj.2021.62.420

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