Study on the Lewis Acid-promoted Aza-Diels - Alder Reaction of Azetidin-2-one-tethered Imines with Siloxydienes in the Asymmetric Synthesis of 2-Aryl(alkyl)-2,3-dihydro-4-pyridones

Poljak, Tanja; Molčanov, Krešimir; Margetić, Davor; Habuš, Ivan (2008) Study on the Lewis Acid-promoted Aza-Diels - Alder Reaction of Azetidin-2-one-tethered Imines with Siloxydienes in the Asymmetric Synthesis of 2-Aryl(alkyl)-2,3-dihydro-4-pyridones. Croatica Chemica Acta, 81 (4). pp. 539-558. ISSN 0011-1643

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Abstract

trans-3-Amino-b-lactams were evaluated as the chiral building blocks in the aza-Diels – Alder reaction of azetidin-2-one-tethered imines with siloxydienes under Lewis acid catalysis, as a route for the asymmetric synthesis of 2-aryl(alkyl)-2,3-dihydro-4-pyridones.

Item Type:	Article
Uncontrolled Keywords:	beta-lactam; imine; pyridone; aza-Diels - Alder reaction; Lewis acid; lactam synthon method; chiral ester enolate; c-13 side-chain; beta-lactams; semiempirical methods; efficient; 2,3-dihydro-4-pyridones; cyclocondensation; cycloaddition; condensation
Subjects:	NATURAL SCIENCES > Chemistry
Divisions:	Division of Organic Chemistry and Biochemistry Division of Physical Chemistry
Projects:	Project title Project leader Project code Project type Amino-beta-laktami - intermedijari u sintezi biološki interesantnih spojeva [70961] Ivan Habuš 098-0982915-2948 MZOS Host-guest međudjelovanja u policikličkim sustavima [161124] Davor Margetić 098-0982933-3218 MZOS
Depositing User:	Ivan Habuš
Date Deposited:	22 Oct 2013 08:17
URI:	http://fulir.irb.hr/id/eprint/818

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