Skelin, Josipa; Sabol, Ivan; Tomaić, Vjekoslav (2022) Do or Die: HPV E5, E6 and E7 in Cell Death Evasion. Pathogens, 11 (9). ISSN 2076-0817
|
PDF
- Published Version
- article
Available under License Creative Commons Attribution. Download (1MB) | Preview |
Abstract
Abstract: Human papillomaviruses (HPVs) infect the dividing cells of human epithelia and hijack the cellular replication machinery to ensure their own propagation. In the effort to adapt the cell to suit their own reproductive needs, the virus changes a number of processes, amongst which is the ability of the cell to undergo programmed cell death. Viral infections, forced cell divisions and mutations, which accumulate as a result of uncontrolled proliferation, all trigger one of several cell death pathways. Here, we examine the mechanisms employed by HPVs to ensure the survival of infected cells manipulated into cell cycle progression and proliferation.
| Item Type: | Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Uncontrolled Keywords: | E5 ; E6 ; E7 ; HPV ; cervical cancer ; apoptosis ; autophagy ; anoikis ; pyroptosis | ||||||||
| Subjects: | NATURAL SCIENCES > Biology BIOMEDICINE AND HEALTHCARE > Basic Medical Sciences |
||||||||
| Divisions: | Division of Molecular Medicine | ||||||||
| Projects: |
|
||||||||
| Depositing User: | Ivan Sabol | ||||||||
| Date Deposited: | 18 Oct 2022 06:41 | ||||||||
| URI: | http://fulir.irb.hr/id/eprint/7589 | ||||||||
| DOI: | 10.3390/pathogens11091027 |
Actions (login required)
 |
View Item |
Altmetric
Altmetric
