Šimatović, Ana; Udiković-Kolić, Nikolina Antibiotic Resistance in Pharmaceutical Industry Effluents and Effluent-Impacted Environments. In: Antibiotic resistance in the environment: a worldwide overview, Edition: The Handbook of Environmental Chemistry. The Handbook of Environmental Chemistry . Springer, Berlin, Heidelberg.
Abstract
Overuse and misuse of antibiotics are likely the leading causes of antibiotic resistance accumulation in human pathogens, but it has in the last decade been recognized that the discharges from antibiotic manufacturing facilities can also contribute. Such discharges have repeatedly been shown to provide conditions where antibiotics reach concentrations that are selective for resistance enrichment. Manufacturing facilities and environments receiving their effluents are, therefore, key to determining the magnitude of antibiotic resistance, as well as identifying the critical control points to slow its emergence and spread. This chapter endeavours to review the recent research in the extent of pollution from antibiotic-producing factories and the effects of this pollution in the external environment. It also provides a case study in Croatia summarizing the discharges from the manufacturing of the antibiotic azithromycin and the subsequent impact these discharges caused to the receiving river.
| Item Type: | Book Section |
|---|---|
| Uncontrolled Keywords: | antibiotic resistance; environmental pollution; manufacturing; pharmaceutical effluent |
| Subjects: | NATURAL SCIENCES > Interdisciplinary Natural Sciences NATURAL SCIENCES > Interdisciplinary Natural Sciences > Environmental Science |
| Divisions: | Division for Marine and Enviromental Research |
| Depositing User: | Milena Milaković Obradović |
| Date Deposited: | 29 Apr 2020 11:29 |
| URI: | http://fulir.irb.hr/id/eprint/5597 |
| DOI: | 10.1007/698_2019_389 |
Actions (login required)
 |
View Item |
Altmetric
Altmetric
