1, 3-Dipolar Cycloaddition (Part I): Synthesis of 1, 2, 3-Triazole Derivatives in Nucleoside Chemistry

Saftić, Dijana; Krstulović, Luka; Bajić, Miroslav; Žinić, Biserka (2015) 1, 3-Dipolar Cycloaddition (Part I): Synthesis of 1, 2, 3-Triazole Derivatives in Nucleoside Chemistry. Kemija u industriji, 64 (9-10). pp. 481-498. ISSN 0022-9830

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Abstract

Copper catalysed Huisgen 1,3-dipolar cycloaddition of azides and alkynes which leads to 1,4-disubstituted-1,2,3-triazoles is a frequently used method in synthetic organic chemistry. Due to the simple reaction conditions, it has occupied an important place in the field of nucleoside chemistry since it enables preparation of a large number of potentially biologically active compounds with a number of interesting additional properties induced by the presence of 1,2,3-triazole structural motif in the molecule.

Item Type:	Article
Uncontrolled Keywords:	Click Chemistry; Nucleosides; 1, 2, 3-Triazole Nucleoside Analogs
Subjects:	NATURAL SCIENCES > Chemistry
Divisions:	Division of Organic Chemistry and Biochemistry
Projects:	Project title Project leader Project code Project type Synthesis of novel biologically active nucleobase and nucleotide derivatives (Sinteza novih biološki aktivnih derivata nukleobaza i nukleotida)- Biserka Žinić 098-0982914-2935 MZOS
Depositing User:	Dijana Pavlović Saftić
Date Deposited:	13 Jun 2016 13:02
URI:	http://fulir.irb.hr/id/eprint/2881
DOI:	10.15255/KUI.2014.020

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