Analysis of Human Kidney Stones Using Advanced Characterization Techniques

Brdarić Kosanović, Jelena; Živković, Kristijan; Šerić, Vatroslav; Marković, Berislav; Szenti, Imre; Kukovecz, Ákos; Matijaković Mlinarić, Nives; Stanković, Anamarija (2024) Analysis of Human Kidney Stones Using Advanced Characterization Techniques. Crystals, 15 (1). ISSN 2073-4352

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Abstract

A comprehensive analysis of kidney stones is essential for the future treatment of patients. Almost all of the methods available for kidney stone analysis were used in this study. The chemical analysis included powder X-ray diffraction (PXRD), Fourier transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA-DSC). Following the chemical analysis, a detailed morphological analysis was carried out using stereoscopic microscopy, scanning electron microscopy (SEM-EDX), and micro-computed tomography (micro-CT). These investigations showed that the sixteen kidney stones analyzed in detail had a heterogeneous mineralogical structure, consisting of at least two different minerals. Kidney stones consist mainly of calcium oxalate (whewellite or weddellite) but also contain significant amounts of phosphate (mainly apatite and struvite). A thorough analysis of kidney stones can determine the cause of their formation and investigate possible treatments.

Item Type:	Article
Uncontrolled Keywords:	kidney stones; calcium oxalate; phosphate; chemical analysis
Subjects:	NATURAL SCIENCES > Chemistry > Inorganic Chemistry BIOMEDICINE AND HEALTHCARE > Pharmacy > Medical Biochemistry
Divisions:	Division of Materials Chemistry
Depositing User:	Ema Buhin Šaler
Date Deposited:	26 Mar 2026 12:38
URI:	http://fulir.irb.hr/id/eprint/11496
DOI:	10.3390/cryst15010006

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