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Fish liver damage related to the wastewater treatment plant effluents

Topić Popović, Natalija; Čižmek, Lara; Babić, Sanja; Strunjak-Perović, Ivančica; Čož-Rakovac, Rozelindra (2023) Fish liver damage related to the wastewater treatment plant effluents. Environmental science and pollution research, 30 . pp. 48739-48768. ISSN 0944-1344

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Wastewater treatment plants (WWTPs) continuously release a complex mixture of municipal, hospital, industrial, and runoff chemicals into the aquatic environment. These contaminants are both legacy contaminants and emerging-concern contaminants, affecting all tissues in a fish body, particularly the liver. The fish liver is the principal detoxifying organ and effects of consistent pollutant exposure can be evident on its cellular and tissue level. The objective of this paper is thus to provide an in-depth analysis of the WWTP contaminants’ impact on the fish liver structure, physiology, and metabolism. The paper also gives an overview of the fish liver biotransformation enzymes, antioxidant enzymes, and non-enzymatic antioxidants, their role in metabolizing xenobiotic compounds and coping with oxidative damage. Emphasis has been placed on highlighting the vulnerability of fish to xenobiotic compounds, and on biomonitoring of exposed fish, generally involving observation of biomarkers in caged or native fish. Furthermore, the paper systematically assesses the most common contaminants with the potential to affect fish liver tissue.

Item Type: Article
Uncontrolled Keywords: WWTP ; Vulnerability ; Stress ; Contaminants ; Biotransformation
Subjects: NATURAL SCIENCES > Biology
Divisions: Division of Materials Chemistry
Project titleProject leaderProject codeProject type
Bioprospecting Jadranskog mora-Igor Jerković; Verica Dragović-Uzelac; Božidar Šantek; Rozelinda Čož-Rakovac; Sandra Kraljević Pavelić; Stela JokićKK.
Depositing User: Natalija Topić Popović
Date Deposited: 11 Oct 2023 13:53
DOI: 10.1007/s11356-023-26187-y

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