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Biomarkers of nitro-oxidation and oxidative stress

Čipak Gašparović, Ana; Žarković, Neven; Bottari, Serge P. (2018) Biomarkers of nitro-oxidation and oxidative stress. Current opinion in toxicology, 7 . pp. 73-80. ISSN 2468-2934

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Macromolecule oxidation in response to reactive oxygen species (ROS) is associated with a variety of diseases. The recognition of NO as a key regulator of redox signalling has more recently led to the discovery that reactive nitrogen species (RNS) also elicit modifications of macromolecules which are also involved in pathophysiological processes. This article provides an overview of key biomarkers used to assess oxidation, peroxidation and nitration/nitrosation signaling, stressing the necessity to analyse multiple biomarkers to understand the redox mechanisms involved in biological responses.

Item Type: Article
Uncontrolled Keywords: oxidative stress, nitrosative stress , ROS, HNE
Subjects: BIOMEDICINE AND HEALTHCARE > Basic Medical Sciences
Divisions: Division of Molecular Medicine
Depositing User: Tea Vuković
Date Deposited: 05 May 2020 08:58
DOI: 10.1016/j.cotox.2017.10.002

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