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Genomics Virtual Laboratory: a practical bioinformatics workbench for the cloud

Afgan, Enis; Sloggett, Clare; Goonasekera, Nuwan; Makunin, Igor; Benson, Derek; Crowe, Mark; Gladman, Simon; Kowsar, Yousef; Pheasant, Michael; Horst, Ron; Lonie, Andrew (2015) Genomics Virtual Laboratory: a practical bioinformatics workbench for the cloud. PLoS ONE, 10 (10). 0140829/1-0140829/20. ISSN 1932-6203

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Analyzing high throughput genomics data is a complex and compute intensive task, generally requiring numerous software tools and large reference data sets, tied together in successive stages of data transformation and visualisation. A computational platform enabling best practice genomics analysis ideally meets a number of requirements, including: a wide range of analysis and visualisation tools, closely linked to large user and reference data sets ; workflow platform(s) enabling accessible, reproducible, portable analyses, through a flexible set of interfaces ; highly available, scalable computational resources ; and flexibility and versatility in the use of these resources to meet demands and expertise of a variety of users. Access to an appropriate computational platform can be a significant barrier to researchers, as establishing such a platform requires a large upfront investment in hardware, experience, and expertise.

Item Type: Article
Uncontrolled Keywords: Genomics Virtual Laboratory; bioinformatics; genome research
Subjects: BIOTECHNICAL SCIENCES > Interdisciplinary Technical Sciences
SOCIAL SCIENCES > Information and Communication Sciences
Divisions: Center for Informatics and Computing
Depositing User: Enis Afgan
Date Deposited: 27 Apr 2016 11:49
DOI: 10.1371/journal.pone.0140829

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