Grce, Magdalena; Husnjak, Koraljka; Matovina, Mihaela; Milutin Gašperov, Nina; Magdić, Lada; Husnjak, Ozren; Pavelić, Krešimir
Human Papillomavirus, Cytomegalovirus and Adeno-associated Virus 2 Infections in Pregnant and Non-Pregnant Women with Cervical Intraepithelial Neoplasia.
Journal of Clinical Microbiology, 42
Two hundred and eight cervical specimens from two groups of subjects, 165 non- and 53 pregnant women with CIN I-III were positive by PCR analyses for human papillomaviruses (HPVs), adeno-associated virus type 2 (AAV 2) and human cytomegalovirus (HCMV) in 67, 6 and 4.1% cases, respectively. The presence of AAV 2 infection was more frequently associated with pregnancy (17% versus 2.4%) and HPV-positive cervices (OR=6.358) than HCMV was. Increased HPV infection was strongly associated (P<0.001) with increased CIN grade, but there is no evidence that AAV 2 and HCMV infections have any impact on the CIN development.
||human papillomavirus; cytomegalovirus; adeno-associated virus type 2; cervical intraepithelial neoplasia
||BIOMEDICINE AND HEALTHCARE > Basic Medical Sciences
||Division of Molecular Medicine
|Project title||Project leader||Project code||Project type|
|Molekularno-genetički i prognostički čimbenici u nastanku raka vrata maternice||Dr.sc. Magdalena Grce||0098104||UNSPECIFIED|
|Određivanje globalnog genskog profila tumora metodom DNA-čipova||Dr.sc. Šime Spaventi||0101023||UNSPECIFIED|
|Utjecaj transdukcije gena/proteina na signalne puteve transformiranih stanica||Dr.sc. Krešimir Pavelić||0098093||UNSPECIFIED|
Nina Milutin Gašperov
||23 Nov 2015 15:48
||01 Dec 2015 11:47
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