Mechanochemical N-alkylation of imides

Briš, Anamarija; Đud, Mateja; Margetić, Davor (2017) Mechanochemical N-alkylation of imides. Beilstein Journal of Organic Chemistry, 2017 (13). pp. 1745-1752. ISSN 1860-5397

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Abstract

The mechanochemical N-alkylation of imide derivatives was studied. Reactions under solvent-free conditions in a ball mill gave good yields and could be put in place of the classical solution conditions. The method is general and can be applied to various imides and alkyl halides. Phthalimides prepared under ball milling conditions were used in a mechanochemical Gabriel synthesis of amines by their reaction with 1,2-diaminoethane.

Item Type:	Article
Uncontrolled Keywords:	ball milling; Gabriel reaction; imides; mechanochemistry; N-alkylation
Subjects:	NATURAL SCIENCES NATURAL SCIENCES > Chemistry NATURAL SCIENCES > Chemistry > Organic Chemistry
Divisions:	Division of Organic Chemistry and Biochemistry
Projects:	Project title Project leader Project code Project type Host-guest međudjelovanja u policikličkim sustavima- Davor Margetić 098-0982933-3218 MZOS Nekovalentne interakcije u dizajnu novih fotoosjetljivih molekula-NoncoPhoto Davor Margetić IP-2013-11-9310 HRZZ
Depositing User:	Anamarija Briš
Date Deposited:	12 Dec 2025 10:05
URI:	http://fulir.irb.hr/id/eprint/10424
DOI:	10.3762/bjoc.13.169

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