Induction of helical chirality in tetrahedral transition metal complexes with non-bridging monodentate oxazolines

Bakija, Marija; Perić, Berislav; Rinkovec, Tamara; Sanders, Ernest; Kokan, Zoran; Štefanić, Zoran; Vianello, Robert; Kirin, Srećko (2025) Induction of helical chirality in tetrahedral transition metal complexes with non-bridging monodentate oxazolines. Dalton Transactions, 54 (46). 17083 -17101. ISSN 1477-9226

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Abstract

Chirality on C4-atoms of non-bridging monodentate oxazolines direct stereoselective formation of helical chirality in [M(1)2X2] tetrahedral metal complexes of zinc(II), cadmium(II) and cobalt(II) halides, as revealed by their crystal structures. This feature was used to prepare a set of helically chiral derivatives with various structural motifs. In particular, bulkiness, non-covalent interactions and choice of point chirality combinations were found to strongly affect induction of chirality on the metal atom. The substituent influence on complexation and chiral induction was analyzed using XRD-diffraction studies, NMR, UV-Vis and CD spectroscopies, as well as DFT calculations.

Item Type:	Article
Uncontrolled Keywords:	helical chirality; metal complexes; monodentate; oxazolines; supramolecular interactions; tetrahedral coordination
Subjects:	NATURAL SCIENCES > Chemistry
Divisions:	Division of Materials Chemistry
Projects:	Project title Project leader Project code Project type Inovativna rješenja u katalitičkim proizvodnim procesima za potrebe farmaceutske industrije-CAT PHARMA Srećko Kirin KK.01.1.1.04.0013 EK Supramolekulska asimetrična kataliza: Prijenos kiralnosti u koordinacijskim kavezima (Cage Cat) Srećko Kirin IP-2022-10-8456 HrZZ
Depositing User:	Marija Bakija
Date Deposited:	26 Nov 2025 12:19
URI:	http://fulir.irb.hr/id/eprint/10234
DOI:	10.1039/d5dt02399h

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