One-Year Comparative Evaluation of Highly Aspherical Lenslets and Horizontally Asymmetric Peripheral Defocus Lenses for Myopia Control in School-Aged Children

Orešković, Ivana; Malenica Ravlić, Maja; Knežević, Lana; Doko Mandić, Blanka; Marić, Goran; Vukojević, Ante; Zorić Geber, Mia; Vatavuk, Zoran; Sabol, Ivan; Škunca Herman, Jelena (2025) One-Year Comparative Evaluation of Highly Aspherical Lenslets and Horizontally Asymmetric Peripheral Defocus Lenses for Myopia Control in School-Aged Children. Life, 15 (7). ISSN 2075-1729

PDF - Published Version - article Available under License Creative Commons Attribution. Download (917kB)

Abstract

Purpose: The aim of this study was to compare the one-year efficacy of three spectacle lens designs, highly aspherical lenslets (HALs), horizontally asymmetric peripheral defocus (HAPD) lenses, and standard single vision lenses (SVLs) in slowing myopia progression in school-aged children. Methods: In this prospective, non-randomized study, 57 children, aged 8–17 years, were grouped based on the type of lenses worn: HAL (n = 16), HAPD (n = 21), or SVL (n = 20). Comprehensive ophthalmologic examinations were performed at baseline, 6 months, and 12 months. Outcome measures included spherical equivalent refraction (SER), spherical refraction (SR), cylindrical refraction (CR), and axial length (AL). Data were analyzed using non-parametric tests with significance set at p < 0.05. Results: All groups showed some progression in SER and AL over 12 months. The HAL group demonstrated the smallest median SER change (−0.3 D), compared to HAPD (−0.5 D) and SVL (−0.4 D), though group differences were not statistically significant (p = 0.111). Axial elongation was significantly lower in the HAL group (0.1 mm, IQR: 0.0–0.2 mm) compared to HAPD and SVL (both 0.2 mm, p < 0.0001). CR remained stable in all groups, with no clinically meaningful changes. The HAPD groups showed no advantages over SVL in any parameter. Conclusions: Among the three lens types studied, HAL lenses were the most effective in reducing both refractive and axial myopia progression over 12 months. These findings support their use as a reliable intervention in pediatric myopia control.

Item Type:	Article
Uncontrolled Keywords:	myopia progression; myopia control; peripheral defocus; axial elongation; highly aspherical lenslets; horizontally asymmetric peripheral defocus lenses; single vision lenses
Subjects:	BIOMEDICINE AND HEALTHCARE > Clinical Medical Sciences > Ophthalmology
Divisions:	Division of Molecular Medicine
Depositing User:	Ivan Sabol
Date Deposited:	02 Sep 2025 08:35
URI:	http://fulir.irb.hr/id/eprint/9945
DOI:	10.3390/life15071119

Actions (login required)

View Item