Gourdon‐Grünewaldt, Lisa; Bakija, Marija; Wild, Lara; Perić, Berislav; Gasser, Gilles; Kirin, Srećko; Cariou, Kevin (2023) Towards Platinum(II) Complexes forin celluloApplications: Synthesis, Characterization, Biological and Catalytic Evaluation. Helvetica Chimica Acta, 106 (8). ISSN 0018-019X
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Abstract
With the aim of achieving bioorthogonal intracellular catalysis, a library of platinum(II) complexes was synthesized. Their non-toxicity to living cells was demonstrated and their catalytic activity was evaluated on a cyclization reaction leading to a highly fluorescent coumarin. None of the platinum complexes showed any catalytic activity for coumarin synthesis. Still, we demonstrated that the silver salt AgSbF6 commonly used to ‘activate’ metal catalysts by removing a chloride is a very efficient catalyst for the studied intramolecular cyclization reaction.
Item Type: | Article | ||||||||
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Uncontrolled Keywords: | chemical biology; catalysis; cyclization; platinum; silver | ||||||||
Subjects: | NATURAL SCIENCES > Chemistry | ||||||||
Divisions: | Division of Materials Chemistry | ||||||||
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Depositing User: | Marija Bakija | ||||||||
Date Deposited: | 05 Dec 2024 15:02 | ||||||||
URI: | http://fulir.irb.hr/id/eprint/9338 | ||||||||
DOI: | 10.1002/hlca.202300078 |
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