hrvatski jezikClear Cookie - decide language by browser settings

Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline

Vušak, Darko; Ležaić, Katarina; Jurec, Jurica; Žilić, Dijana; Prugovečki, Biserka (2022) Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline. Heliyon, 8 (6). ISSN 24058440

[img] PDF - Published Version - article
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (2MB)


Solution-based and solid-state reactions of copper(ii) compounds, 1,10-phenanthroline and l-threonine were investigated. Eight new ternary coordination compounds were obtained: [Cu(l-Thr)(H2O)(phen)]2SO4∙10H2O (1a∙10H 2 O), [Cu(l-Thr)(H2O) (phen)]2SO4∙4.3H2O (1a∙4.3H 2 O), {[Cu(μ-l-Thr)(phen)]2SO4∙3.5H2O} n (1b∙3.5H 2 O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4∙2H2O∙CH3OH (1c∙2H 2 O∙CH 3 OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4∙4H2O (1c∙4H 2 O), [Cu(l-Thr)(CH3OH)(phen)]2SO4∙H2O (1d∙H 2 O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)][Cu(SO4)(l-Thr)(phen)]HSO4∙H2O∙3CH3OH (1e·H 2 O·3CH 3 OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(phen)(py)]SO4 (1f) (phen = 1,10-phenanthroline, l-Thr = l-threoninate, py = pyridine). X-ray crystal structure analysis of the prepared ternary coordination compounds revealed extensive hydrogen bonding and π-interactions that link complex species, anions and solvent molecules into 3D architectures. The water/methanol solvent molecules are found in pockets and/or channels in seven solvates. ESR spectra of different types of compounds were also investigated. In all measured compounds the unpaired electron of the copper(II) ion is located in the dx2-y2 orbital which is in agreement with elongated square-pyramidal geometry. Compound 1a∙10H 2 O showed substantial cytotoxic activity toward human hepatocellular carcinoma (HepG2) and acute monocytic leukaemia (THP-1) cell lines.

Item Type: Article
Uncontrolled Keywords: 1,10-Phenanthroline; Copper complexes; Crystal structures; ESR spectra; Mechanochemical synthesis; Solution-based synthesis; Solvatomorphs; Ternary coordination compounds; l-threonine
Subjects: NATURAL SCIENCES > Chemistry
Divisions: Division of Physical Chemistry
Project titleProject leaderProject codeProject type
Studija važnosti spinskih međudjelovanja kao osnova za nove pristupe u istraživanju materijalaMarina Ilakovac KvederIP-2018-01-3168Znanstveno-istraživački projekti
Centar izvrsnosti u kemiji - CIuKJosip PožarKK. projekti
Depositing User: Diana Mikoč Radešić
Date Deposited: 24 Jan 2024 14:50
DOI: 10.1016/j.heliyon.2022.e09556

Actions (login required)

View Item View Item


Downloads per month over past year

Increase Font
Decrease Font
Dyslexic Font