Changes in Acute Phase Response Biomarkers in Racing Endurance Horses

Mihelić, Karla; Vrbanac, Zoran; Bojanić, Krunoslav; Kostanjšak, Tara; Ljubić, Blanka Beer; Gotić, Jelena; Vnuk, Dražen; Bottegaro, Nika Brkljača (2022) Changes in Acute Phase Response Biomarkers in Racing Endurance Horses. Animals, 12 (21). p. 2993. ISSN 2076-2615

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Abstract

This study aimed to evaluate if exercise-induced acute phase response (APR) occurs in endurance horses in response to the race. The study included 23 horses competing in an endurance competition with a successfully passed clinical examination before the race. Blood samples were collected before the start and within 30 min after the end of the race. Haematological and biochemical tests were performed and correlated to acute phase biomarkers changes. Values of calprotectin and haptoglobin (Hp) decreased after the races compared to values before, while concentrations of ceruloplasmin and albumin recorded a significant increase. Greater changes in calprotectin values were noted in Arabian horses compared to other breeds. Values of Hp showed a significantly greater decrease after longer races. Based on study results, endurance racing induces APR in horses characterised by significant changes in selected acute phase biomarkers. More pronounced changes were noted at races with higher average speeds, suggesting the need for thorough horse monitoring during exhausting races.

Item Type:	Article
Uncontrolled Keywords:	equine sport; acute phase biomarkers; acute phase response; calprotectin; endurance race
Subjects:	NATURAL SCIENCES > Biology BIOMEDICINE AND HEALTHCARE > Veterinary Medicine
Divisions:	Division of Materials Chemistry
Depositing User:	Lorena Palameta
Date Deposited:	13 Dec 2023 12:54
URI:	http://fulir.irb.hr/id/eprint/8300
DOI:	10.3390/ani12212993

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