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Burden and prevention of HPV related diseases: Situation in Croatia

Grce, Magdalena; Sabol, Ivan; Milutin Gašperov, Nina (2012) Burden and prevention of HPV related diseases: Situation in Croatia. Periodicum Biologorum, 114 (2). pp. 175-186. ISSN 0031-5362

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The role of persistent infection of high-risk human papillomaviruses (HR-HPV) in cervical cancer has become convincingly established. Other anogenital cancers in women and men are also caused, to a lesser extent, by HR-HPV. In addition, most of the benign anogenital warts and laryngeal papillomatosis are caused by low-risk (LR) HPV types. All these HPV-associated diseases represent high public health burden worldwide, cervical cancer being the leading one. Nowadays, several opportunities are available to prevent cervical cancer and other HPV-related diseases. The most promising cancer preventing intervention is the HPV vaccination against the most common HPV types (16 and 18). However, secondary prevention like education and early detection of the disease by screening have demonstrated in the past great efficacy and should be continued and improved by novel prognostic methods (HPV testing and other biomarkers) in countries where it is already in place and implement in those countries that are lacking cancer control programmes. Herein, the current knowledge on HPVs, HPV-related diseases and their preventive approaches are discussed. In addition, the situation in Croatia is presented.

Item Type: Article
Uncontrolled Keywords: cervical cancer; vulvar cancer; anal cancer; penile cancer; oropharyngeal cancer; genital warts; laryngeal papillomatosis; human papillomavirus; HPV; screening; vaccination; Croatia
Subjects: BIOMEDICINE AND HEALTHCARE > Basic Medical Sciences
Divisions: Division of Molecular Medicine
Project titleProject leaderProject codeProject type
Aberrant DNA methylation in HPV associated lesions (Promijenjeno stanje DNA-metilacije u HPV-povezanim oštećenjima)Magdalena Grce098-0982464-2510MZOS
Depositing User: Nina Milutin Gašperov
Date Deposited: 20 Nov 2015 14:56

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