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Variation in satellite DNA profiles - causes and effects

Ugarković, Đurđica; Plohl, Miroslav (2002) Variation in satellite DNA profiles - causes and effects. EMBO Journal, 21 (22). pp. 5955-5959. ISSN 0261-4189

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Heterochromatic regions of the eukaryotic genome harbour DNA sequences that are repeated many times in tandem, collectively known as satellite DNAs. Different satellite sequences coexist in the genome thus forming a set called a satellite DNA library. Within a library, satellite DNAs represent independent evolutionary units. Their evolution can be explained as a result of change in two parameters: copy number and nucleotide sequence, both of them ruled by the same mechanisms of concerted evolution. Individual change in either of these two parameters as well as their simultaneous evolution can lead to the genesis of species-specific satellite profiles. In some cases changes in satellite DNA profiles can be correlated with chromosomal evolution and could possibly influence the evolution of species.

Item Type: Article
Uncontrolled Keywords: concerted evolution; repetitive DNA; satellite DNA library
Subjects: NATURAL SCIENCES > Biology
Divisions: Division of Molecular Biology
Depositing User: Đurđica Ugarković
Date Deposited: 03 Mar 2015 15:39
DOI: 10.1093/emboj/cdf612

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