Biomimetic preparation and properties of silver nanoparticles/calcium phosphates composites and composite coatings on the titanium surface

Inkret, Suzana (2025) Biomimetic preparation and properties of silver nanoparticles/calcium phosphates composites and composite coatings on the titanium surface. Doctoral thesis, Sveučilište u Zagrebu, Prirodoslovno-matematički fakultet.

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Abstract

Composites of calcium phosphates and nanomaterials with antimicrobial properties are considered an effective approach for the prevention and treatment of infections caused by implantation. Silver nanoparticles are attracting attention due to their broad antibacterial activity and low potential to cause bacterial resistance. Although the biomimetic method for the preparation of calcium phosphates/silver nanoparticels composites is economical, ecological, and accepted as a “green“ method of preparation that enables the coating of implants with complex shapes, it has not yet been fully explored. For this reason, the biomimetic preparation of calcium phosphates composites with silver nanoparticles modified with different stabilizers (sodium bis(2˗ethylhexyl) sulfosuccinate, poly(vinylpyrrolidone), and trisodium citrate) and of multicomponent calcium phosphates/silver nanoparticles composites with bovine serum albumin or chitosan was investigated in this work. The characterization showed a significant influence of silver nanoparticles, albumin and chitosan on the transformation of amorphous into crystalline precipitates and their morphology. In addition, calcium phosphates/silver nanoparticles composite coatings with/without albumin or chitosan were biomimetically prepared on differently etched titanium surfaces. The results showed a greater uniformity of the coatings on a rougher surface and an improvement in the wetting properties of the surfaces after coating.

Item Type:	Thesis (Doctoral thesis)
Uncontrolled Keywords:	biomacromolecules; calcium phosphates; composites; precipitation; silver nanoparticles; surface modification; titanium implants
Subjects:	NATURAL SCIENCES > Chemistry > Physical Chemistry NATURAL SCIENCES > Chemistry > Inorganic Chemistry
Divisions:	Division of Physical Chemistry
Projects:	Project title Project leader Project code Project type Mehanizmi nastajanja kalcijevih fosfata na anorganskim nanomaterijalima. Biomimetski put priprave multifunkcionalnih kompozita za regeneraciju čvrstih tkiva-CaPBiomimNanocomp Maja Dutour Sikirić IP-2018-01-1493 HRZZ Program mobilnosti - odlazna mobilnost asistenata Suzana Inkret MOBDOK-2023-4472 UNSPECIFIED
Depositing User:	Suzana Inkret
Date Deposited:	12 Feb 2026 09:39
URI:	http://fulir.irb.hr/id/eprint/11229

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