Genetic Basis of Stress-Related Neuropsychiatric Disorders

Švob Štrac, Dubravka (2024) Genetic Basis of Stress-Related Neuropsychiatric Disorders. Genes, 15 (10). ISSN 2073-4425

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Abstract

Stress exposure is one of the major risk factors for the development of different psychiatric and neurodegenerative diseases, leading to various (mal)adaptive alternations in different parts of the brain, and affecting both brain structure and function [1,2]. However, other determinants (social, biological, genetic) could distinguish between persons who are at higher risk to develop neuropsychiatric disorders after exposure to stress from resilient individuals [3,4]. Hence, the identification of (epi)genetic underpinnings of resilience and vulnerability to stress is necessary in order to better understand the etiology of stress-related neuropsychiatric disorders, as well as to improve preventive and therapeutic strategies [5,6]. In the Special Issue “Genetic Basis of Stress-Related Neuropsychiatric Disorders”, we have collected a series of nine published papers, including five original research papers, three comprehensive literature reviews and one novel hypothesis. These articles cover different aspects of research in the field of genetics, pharmacogenetics, epigenetics, genomics, transcriptomics and proteomics, post-traumatic stress disorder (PTSD), anxiety and mood disorders, substance use disorders, schizophrenia and attention deficit hyperactivity disorder (ADHD).

Item Type:	Article
Uncontrolled Keywords:	stress; neuropsychiatric disorders; therapeutic strategies
Subjects:	BIOMEDICINE AND HEALTHCARE > Clinical Medical Sciences > Psychiatry
Divisions:	Division of Molecular Medicine
Depositing User:	Ema Buhin Šaler
Date Deposited:	21 Apr 2026 14:29
URI:	https://fulir.irb.hr:/id/eprint/11776
DOI:	10.3390/genes15101274

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