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Neutral rhodol-based dyes expressing localization in mitochondria

Ferraboschi, Ilaria; Ovčar, Juraj; Vygranenko, Kateryna V.; Yu, Shupei; Minervino, Alfonso; Wrzosek, Antoni; Szewczyk, Adam; Rozza, Riccardo; Magistrato, Alessandra; Belfield, Kevin D.; Gryko, Daniel T.; Grisanti, Luca; Sissa, Cristina (2024) Neutral rhodol-based dyes expressing localization in mitochondria. Organic & Biomolecular Chemistry, 22 (29). pp. 5886-5890. ISSN 1477-0520

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Abstract

Neutral rhodol-based red emitters are shown to efficiently localize in mitochondria, as demonstrated by confocal microscopy and co-localization studies. A simple model is proposed to explain the localization mechanism of neutral molecules. The model takes into account the strong coupling between the molecular dipole moment and the electric field of the inner mitochondrial membrane.

Item Type: Article
Uncontrolled Keywords: hydrophobic ion interactions; fluorescent-probes; permeability; transport; membranes; dynamics; cations
Subjects: NATURAL SCIENCES > Chemistry > Organic Chemistry
NATURAL SCIENCES > Biology > Biochemistry and Molecular Biology
Divisions: Division of Experimental Physics
Theoretical Physics Division
Projects:
Project titleProject leaderProject codeProject type
Multifunkcionalni nanonosači za nelinearnu mikroskopiju: novi alati za biologiju i medicinuIvor Lončarić101007804EK
Depositing User: Ema Buhin Šaler
Date Deposited: 16 Apr 2026 11:45
URI: http://fulir.irb.hr/id/eprint/11731
DOI: 10.1039/d4ob00252k

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