The ABCD grading system in assessment of corneal cross-linking effect in keratoconus with different cone locations

Krolo, Iva; Kasumović, Aida; Matoc, Ines; Sabol, Ivan; Radman, Ivana; Ratković, Mirko (2021) The ABCD grading system in assessment of corneal cross-linking effect in keratoconus with different cone locations. Journal of Optometry . ISSN 1888-4296 (In Press)

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Abstract

Purpose The aim of this study was to analyse the postoperative corneal cross-linking results of corneal parameters and the ABCD grading system, depending on the cone location. Methods Thirty eyes of 25 patients with keratoconus (KC), who received the corneal cross-linking (CXL) treatment, were included in this study. The exclusion criteria were: patients under 18 years of age, corneal pachymetry less than 400 μm, corneal scarring, history of ocular trauma, history of ocular surgery, and corneal pathology other than KC. Patients were examined at the baseline visit, and followed-up at three, six, and twelve months after the CXL. All patients underwent visual acuity and Scheimpflug tomography at all visits. Progression parameters, keratometries, and ABCD grading were compared between the visits. Patients were classified into two groups: central and paracentral cones group (within the central 5 mm corneal zone) and peripheral cones group (outside the central 5 mm corneal zone), based on X-Y coordinates of maximal keratometry (Kmax). Results Parameter A remained relatively stable throughout the follow-up period in both groups. Parameter B and parameter C showed a significant increase in both groups postoperatively. Parameter D showed stability at the 6-month post-CXL visit in the peripheral KC group, while the central and paracentral KC group showed improvement at the 12-month post-CXL visit. Conclusion There was no significant difference in the postoperative response between different cone locations in the ABCD grading system, when classifying according to the Kmax, except an earlier recovery of the parameter D in peripherally located cones.

Item Type:	Article
Uncontrolled Keywords:	keratoconus; corneal cross-linking; ABCD grading system; corneal tomography
Subjects:	BIOMEDICINE AND HEALTHCARE > Clinical Medical Sciences BIOMEDICINE AND HEALTHCARE > Clinical Medical Sciences > Ophthalmology
Divisions:	Division of Molecular Medicine
Depositing User:	Ivan Sabol
Date Deposited:	06 Apr 2022 07:43
URI:	http://fulir.irb.hr/id/eprint/7166
DOI:	10.1016/j.optom.2021.09.002

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