Trapping reactive intermediates by mechanochemistry : elusive aryl N-Thiocarbamoylbenzotriazoles as bench-stable reagents

Štrukil, Vjekoslav; Gracin, Davor; Magdysyuk, Oxana V.; Dinnebier, Robert E.; Friščić, Tomislav (2015) Trapping reactive intermediates by mechanochemistry : elusive aryl N-Thiocarbamoylbenzotriazoles as bench-stable reagents. Angewandte Chemie International Edition, 54 (29). pp. 8440-8443. ISSN 1433-7851

Preview

PDF - Accepted Version - article Download (1MB) | Preview

Abstract

Monitoring of mechanochemical thiocarbamoylation by in situ Raman spectroscopy revealed the formation of aryl N-thiocarbamoylbenzotriazoles, reactive intermediates deemed unisolable in solution. The first-time isolation and structural characterization of these elusive molecules demonstrates the ability of mechanochemistry to access otherwise unobtainable intermediates and offers a new range of masked isothiocyanate reagents.

Item Type:	Article
Uncontrolled Keywords:	mechanochemistry; reactive intermediates; thiocarbamoylation; thiourea
Subjects:	NATURAL SCIENCES NATURAL SCIENCES > Chemistry
Divisions:	Division of Organic Chemistry and Biochemistry
Depositing User:	Vjekoslav Štrukil
Date Deposited:	08 Dec 2016 15:33
URI:	http://fulir.irb.hr/id/eprint/3178
DOI:	10.1002/anie.201502026

Actions (login required)

View Item