Turn-on fluorescence of ruthenium pyrene complexes in response to bovine serum albumin

Opačak, Saša; Pernar Kovač, Margareta; Brozović, Anamaria; Piantanida, Ivo; Kirin, Srećko I. (2023) Turn-on fluorescence of ruthenium pyrene complexes in response to bovine serum albumin. Dalton Transactions, 52 (33). pp. 11698-11704. ISSN 1477-9226

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Abstract

Two novel pyrene triphenylphosphine ruthenium conjugates act as fluorescent turn-on beacons for serum albumin, being non-fluorescent in aqueous media but exhibiting strong emission upon binding to BSA. The selective cytotoxicity of compounds against tumour cells is enhanced upon irradiation by UV-light, paving the avenue for application in photodynamic therapy under two-photon excitation.

Item Type:	Article
Uncontrolled Keywords:	ruthenium complexes; bovine serum albumin; cytotoxicity; photodynamic therapy
Subjects:	NATURAL SCIENCES NATURAL SCIENCES > Chemistry NATURAL SCIENCES > Biology > Biochemistry and Molecular Biology
Divisions:	Division of Materials Chemistry Division of Molecular Biology Division of Organic Chemistry and Biochemistry
Projects:	Project title Project leader Project code Project type Inovativna rješenja u katalitičkim proizvodnim procesima za potrebe farmaceutske industrije-CAT PHARMA Srećko Kirin KK.01.1.1.04.0013 EK Višekromoforne probe za prepoznavanje pojedinih struktura DNA, RNA i proteina-BioMultiChromoProbes Ivo Piantanida IP-2018-01-5475 HRZZ
Depositing User:	Ivo Piantanida
Date Deposited:	12 Jul 2024 11:19
URI:	http://fulir.irb.hr/id/eprint/8943
DOI:	10.1039/d3dt02289g

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