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The Increased Release Kinetics of Quercetin from Superparamagnetic Nanocarriers in Dialysis

Mandić, Lucija; Matković, Marija; Baranović, Goran; Šegota, Suzana (2023) The Increased Release Kinetics of Quercetin from Superparamagnetic Nanocarriers in Dialysis. Antioxidants, 12 (3). pp. 732-748. ISSN 2076-3921

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Abstract

The actual cumulative mass of released quercetin from nanoparticles within the dialysis membrane was determined under the influence of external stationary and alternating magnetic fields. We have shown that the control of the release kinetics of quercetin from MNPs, i.e., the distribution of quercetin between the nanoparticles and the suspension within the membrane, can be tuned by the simple combination of stationary and alternating magnetic fields. Under non-sink conditions, the proportion of quercetin in the suspension inside the membrane is increased toward the nanoparticles, resulting in the increased release of quercetin. The results obtained could be applied to the release of insoluble flavonoids in aqueous suspensions in general.

Item Type: Article
Uncontrolled Keywords: release kinetics ; superparamagnetism ; stationary magnetic field ; alternating magnetic fields ; magnetic nanoparticles ; quercetin ; viscosity
Subjects: NATURAL SCIENCES > Physics
NATURAL SCIENCES > Chemistry
BIOMEDICINE AND HEALTHCARE > Pharmacy
INTERDISCIPLINARY AREAS OF KNOWLEDGE > Biotechnology in Biomedicine (natural science, biomedicine and healthcare, bioethics area
Divisions: Division of Organic Chemistry and Biochemistry
Division of Physical Chemistry
Projects:
Project titleProject leaderProject codeProject type
Zaštitni mehanizmi i učinci flavonoida ugrađenih u nanonosače u modelnim membranama i neuronimaŠegota, SuzanaIP-2016-06-8415HRZZ
Depositing User: Suzana Šegota
Date Deposited: 21 Jun 2023 07:57
URI: http://fulir.irb.hr/id/eprint/8047
DOI: 10.3390/antiox12030732

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