Škrtić, Anita; Jakšić, Ozren; Ostojić, Slobodanka; Antica, Mariastefania; Crnković, Petra; Josipa, Skelin; Jurenec, Silvana; Habijanec, Borna; Radic Kristo, Delfa (2021) Association between BCL2, BCL2 E17, MCL1 and BAX Protein Expression, Bone Marrow Microenvironment Histological Features, Clinical Presentation, Therapeutic Outcome, and the Overall Survival in Newly Diagnosed Multiple Myeloma. Blood, 138 (4716). ISSN 0006-4971
|
PDF
- Accepted Version
- poster
Download (564kB) | Preview |
Abstract
We evaluated the correlation between immunohistochemical BCL2, BCL2 E17, MCL1 (Bcl2-related protein family) and BAX (effector proapoptotic protein) expression and intensity of staining in plasma cells (PC) in MM patients (pts) who were eligible for autologous stem cell transplantation (ASCT) with DD4, CD8, and FOXP3 positive Tregs lymphocytes in bone marrow (BM) microenvironment, morphologic features of PC, clinical parameters, and outcomes.
| Item Type: | Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Uncontrolled Keywords: | Multiple Myeloma ; stem cells ; BCL-2 ; Bone Marrow Microenvironment | ||||||||
| Subjects: | BIOMEDICINE AND HEALTHCARE BIOMEDICINE AND HEALTHCARE > Basic Medical Sciences > Cytology, Histology and Embryology BIOMEDICINE AND HEALTHCARE > Basic Medical Sciences > Immunology BIOMEDICINE AND HEALTHCARE > Clinical Medical Sciences > Clinical Cytology |
||||||||
| Divisions: | Division of Molecular Biology | ||||||||
| Projects: |
|
||||||||
| Depositing User: | Mariastefania Antica | ||||||||
| Date Deposited: | 16 Mar 2022 09:32 | ||||||||
| URI: | http://fulir.irb.hr/id/eprint/7065 | ||||||||
| DOI: | doi.org/10.1182/blood-2021-154486 |
Actions (login required)
 |
View Item |
Altmetric
Altmetric
