Gamberger, Dragan; Zenko, Bernard; Mitelpunkt, Alexis; Shachar, Netta; Lavrac, Nada (2016) Clusters of male and female Alzheimer's disease patients in the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. Brain Informatics, 3 (3). pp. 169-179. ISSN 2198-4018
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Abstract
This paper presents homogeneous clusters of patients, identified in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) data population of 317 females and 342 males, described by a total of 243 biological and clinical descriptors. Clustering was performed with a novel methodology, which supports identification of patient subpopulations that are homogeneous regarding both clinical and biological descriptors. Properties of the constructed clusters clearly demonstrate the differences between female and male Alzheimer’s disease patient groups. The major difference is the existence of two male subpopulations with unexpected values of intracerebral and whole brain volumes.
| Item Type: | Article | ||||||||
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| Uncontrolled Keywords: | Alzheimer’s disease ; Clustering ; Female and male subpopulations | ||||||||
| Subjects: | TECHNICAL SCIENCES > Computing BIOMEDICINE AND HEALTHCARE > Basic Medical Sciences |
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| Divisions: | Division of Electronics | ||||||||
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| Depositing User: | Dragan Gamberger | ||||||||
| Date Deposited: | 05 Apr 2018 15:44 | ||||||||
| URI: | http://fulir.irb.hr/id/eprint/4008 | ||||||||
| DOI: | 10.1007/s40708-016-0035-5 |
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