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Solvent-Free Mechanochemical Deprotection of N-Boc Group

Margetić, Davor; Đud, Mateja (2017) Solvent-Free Mechanochemical Deprotection of N-Boc Group. International Journal of Organic Chemistry, 7 (2). pp. 140-144. ISSN 2161-4687

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Boc protection group could be readily removed in a very mild mechanochemical conditions. In a short reaction time, ball milling of Boc-protected amines with p-toluenesulfonic acid in solvent-free conditions affords corresponding amine p-TsOH salts.

Item Type: Article
Uncontrolled Keywords: organic synthesis ; mechanochemistry ; deprotection
Subjects: NATURAL SCIENCES > Chemistry
Divisions: Division of Organic Chemistry and Biochemistry
Project titleProject leaderProject codeProject type
Nekovalentne interakcije u dizajnu novih fotoosjetljivih molekula-NoncoPhotoDavor MargetićIP-2013-11-9310HRZZ
Depositing User: Davor Margetić
Date Deposited: 03 Apr 2018 10:43
DOI: 10.4236/ijoc.2017.72011

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