Solvent-Free Mechanochemical Deprotection of N-Boc Group

Margetić, Davor; Đud, Mateja (2017) Solvent-Free Mechanochemical Deprotection of N-Boc Group. International Journal of Organic Chemistry, 7 (2). pp. 140-144. ISSN 2161-4687

Preview

PDF - Published Version - article Available under License Creative Commons Attribution. Download (326kB) | Preview

Abstract

Boc protection group could be readily removed in a very mild mechanochemical conditions. In a short reaction time, ball milling of Boc-protected amines with p-toluenesulfonic acid in solvent-free conditions affords corresponding amine p-TsOH salts.

Item Type:	Article
Uncontrolled Keywords:	organic synthesis ; mechanochemistry ; deprotection
Subjects:	NATURAL SCIENCES > Chemistry
Divisions:	Division of Organic Chemistry and Biochemistry
Projects:	Project title Project leader Project code Project type Nekovalentne interakcije u dizajnu novih fotoosjetljivih molekula-NoncoPhoto Davor Margetić IP-2013-11-9310 HRZZ
Depositing User:	Davor Margetić
Date Deposited:	03 Apr 2018 10:43
URI:	http://fulir.irb.hr/id/eprint/4003
DOI:	10.4236/ijoc.2017.72011

Actions (login required)

View Item