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An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1, 3-bis(2-chloro-4-nitrophenyl)-1E-triazene

Molčanov, Krešimir; Polanc, Slovenko; Osmak, Maja; Kojić-Prodić, Biserka (2015) An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1, 3-bis(2-chloro-4-nitrophenyl)-1E-triazene. Acta Chimica Slovenica, 62 (2). pp. 371-377. ISSN 1318-0207

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Abstract

Biologically active 4-nitro-substituted 1, 3-diaryltriazene, a chemical analogue of 1, 3-bis(4'-amidinophenyl)-triazene-berenil®, belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNA.

Item Type: Article
Uncontrolled Keywords: axial chirality; enantiomeric disorder; molecular structure; crystal structure
Subjects: NATURAL SCIENCES > Chemistry
Divisions: Division of Physical Chemistry
Projects:
Project titleProject leaderProject codeProject type
Cell response to cytotoxic agents and resistance development (Stanični odgovor na citotoksične spojeve i razvoj otpornosti)-Maja Osmak098-0982913-2748MZOS
Protein-ligand interactions at atomic level (Protein-ligand međudjelovanja na atomnoj razini)-Marija Luić098-1191344-2943MZOS
Depositing User: Krešimir Molčanov
Date Deposited: 06 Jul 2016 14:04
Last Modified: 06 Jul 2016 14:04
URI: http://fulir.irb.hr/id/eprint/2899
DOI: 10.17344/acsi.2015.14

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